Plenary and Semi-Plenary Lectures
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| Title: |
| Computational Hemodynamic Study of Cerebral Aneurysms |
| Lecturer: |
| Marie Oshima |
| Abstract: |
| It is known that hemodynamics plays an important role in formation, growth, and rupture of cerebral aneurysms. Particularly, mechanical stresses such as blood-flow induced wall shear stresses are essential factors. In order to obtain a better understanding of their mechanism, this paper focuses on investigation of cerebral hemodynamics and its effects on aneurismal wall. The paper mainly comprises two types of numerical analyses. Since it is important to obtain the detailed information on the hemodynamic properties in the cerebral circulatory system, the first part discusses a large-scale hemodynamic simulation of the Cerebral Arterial Circle of Willis. The second part presents the simulation of cerebral aneurysms with the consideration of blood flow-arterial wall interaction. Both simulations in the first and the second parts are conducted in a patient specific manner using medical images and also include modeling of boundary conditions to emulate realistic hemodynamic conditions. The present mathematical model, however, includes only macroscopic mechanical functions. Therefore, the paper touches upon on future prospects in modeling of microscopic functions such as the effects of endothelial cells and multi physic functions such as physiological effects. |
 Dr. Marie Oshima graduated from Department of Mechanical Engineering, Tsukuba University in March 1984. After receiving Master Degree from Department of Nuclear Engineering at the University of Tokyo in March 1986, she studied at MIT in Department of Nuclear Engineering from September 1986 to January 1990 and received Engineer's Degree in January 1990. She returned to the University of Tokyo and received Ph.D. from the University of Tokyo in March 1992.
Dr. Oshima worked at Institute of Industrial Science (IIS), University of Tokyo as Research Associate from April 1992, and became Assistant Professor in June 1998. She also worked at Stanford University as Visiting Scholar from March 1995 to March 1996. She was promoted to Associate Professor in April 1999 and became Joint Associate Professor at Tsukuba University and IIS, University of Tokyo from April 1999 to March 2000. She returned to IIS, University of Tokyo in 2000 as Associate Professor and became Professor in July 2005.
Dr. Oshima has been engaged in computational hemodynamics such as medical-image based cerebrovasculr flow simulation, and blood flow-arterial wall interactions. She has been also working on flow visualization and measurements using micro PIV techniques for bio- and micro-flow related problems. Dr. Oshima published over 60 papers and 2 textbooks. She gave over 40 presentations at international conferences. Dr. Oshima is on the editorial boards of Journal of Visualization and is an active member of JSME (Japanese Society of Mechanical Engineers). |
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